users are invited to download the software now.
The software is available to companies via a non-exclusive license. Further
information regarding licensing is available by contacting the authors. Companies
are however free to download the software for a 30 day trial. If you wish
to use the software beyond the 30 days
you must take the appropriate licensing steps. If you do not wish to continue
using the software after the trial period, you should remove it from all computers on which you
have installed it.
Commercial users or non-commercial users who would like to have the "Professional"
version with additional features should follow the "BUY LICENSE" link to the left for further informations and easy on-line registration.
read the following disclaimer carefully before proceed with the download,
by ordering the Freeware version of MeltCalc© you accept the following
terms and conditions:
is © 1999 by Ekkehard Schütz & Nicolas von Ahsen. All rights
reserved. No warranties are made as to its correctness or functionality.
Usage at your own risk and for research purposes only. Probe sets
suggested by this program may not be working properly due to intrinsic
properties of the investigated DNA sequence. Please report problems,
errors or program bugs in written form to the authors.
The following references describe the MeltCalc program and its first
application to hybridization assays on the LightCycler. The first
reference should be cited whenever publications report results obtained
with MeltCalc. Both references should be cited when the application
was on the LightCycler:
(1) Schütz,E. and N.von Ahsen. 1999. Spreadsheet software for thermodynamic
melting point prediction of oligonucleotide hybridization with and
without mismatches. Biotechniques
(2) von Ahsen,N., M.Oellerich, V.W.Armstrong and E.Schütz. 1999. Application
of a thermodynamic nearest-neighbor model to estimate nucleic acid
stability and optimize probe design: Prediction of melting points
of different mutations of apolipoprotein B 3500 and factor V Leiden
with a hybridization probe genotyping assay on the LightCycler. Clin
This software is provided on an "as is" basis. The authors of the
software disclaim all warranties relating to this software, whether
express or implied, including but not limited to any implied warranties
of merchantability or fitness for a particular purpose. Neither the
authors nor anyone else who has been involved in the creation, production,
or delivery of this software shall be liable for any indirect, consequential,
or incidental damages arising out of the use or inability to use such
software, even if the authors have been advised of the possibility
of such damages or claims. The person using the software bears all
risk as to the quality and performance of the software. MeltCalc may
not be distributed as part of or for use with any commercial product
without express written permission from the authors. The program may
not be resold, modified for resale, or used to manufacture commercial
products without written approval of the authors.
// Copyright by E.Schuetz | www.MeltCalc.com
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